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Synonym: Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-
CAS Number: 51-55-8
Empirical Formula (Hill Notation): C17H23NO3
Molecular Weight: 289.37
Beilstein Registry Number: 91260
EC Number: 200-104-8
MDL number: MFCD00022622
| Related Categories | AN-AZ, Bioactive Small Molecules, Cell Biology |
| assay | ≥95.0% (NT) |
| ign. residue | ≤0.05% |
| mp | 115-118 °C |
Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.
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| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H300-H330 |
| Precautionary statements | P260-P264-P284-P301 + P310-P310 |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+ |
| Risk Statements | 26/28 |
| Safety Statements | 25-45 |
| RIDADR | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | CK0700000 |
Walch, L., et al., Evidence for a M1 muscarinic receptor on the endothelium of human pulmonary veins. Br. J. Pharmacol. 130, 73-78, (2000)
Zwart, R., and Vijverberg, H.P., Potentiation and inhibition of neuronal nicotinic receptors by atropine: competitive and noncompetitive effects. Mol. Pharmacol. 52, 886-895, (1997)
Trovero, F., et al., Pharmacological profile of CEB-1957 and atropine toward brain muscarinic receptors and comparative study of their efficacy against sarin poisoning. Toxicol. Appl. Pharmacol. 150, 321-327, (1998)
Merck 14,875
Beil. 21,V,1,235
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